A member of the liliaceae family, garlic allium sativum is highly regarded throughout the world for both its medicinal and culinary value. Efficacy of crude extracts of garlic allium sativum linn. The phytochemical screening of the garlic for various phytochemical constituents was conducted using laboratory method. In some varieties, a central scape topped by an umbel of pinkishwhite flowers rises from each clump of leaves to 18 tall in summer. The beneficial health effects of garlic are well documented, including its reduction of blood clotting that is observed at high concentrations berginc and kristl, 20. Rashmi sharma published on 20191126 download full article with reference data and citations. Materials and methods plant material the bulbs of allium stipitatum regel were collected from mount sabzekoh, chaharmahalebakhtiari province of iran during fall 2014 at 2510 m above sea level. The generic name allium is the latin word for garlic, and the type species for the genus is allium sativum which means cultivated garlic. The chemical compositions of the volatile oils of garlic. Determining the chemical compositions of garlic plant and. It has been reported to possess several biological properties including anticarcinogenic, antioxidant. This book provides research on the chemical constituents, medicinal uses and health benefits of allium sativum.
Allium cepa, allium sativum, phytochemical screening, essential oils. Chemical composition, antibacterial and antioxidant. Chemical composition, phytochemical and mineral profile of garlic allium sativum. Description of the herbal substances, herbal preparations or combinations thereof the aim of this report is to assess the non clinical and clinical data available on allium sa tivum for preparing a european union herbal monograph. The determinant effects of preharvest genotype and. Ferreira2 1department of agriculture crop production and rural environment, university of thessaly, fytokou str, 38446, nea ionia, magnesia, greece. Therapeutic uses and pharmacological properties of garlic. Macroscopic and microscopic study of allium sativum. Quantitatively, alkaloid was found to be the abundant constituent making about 7.
Chemical constituents of three allium species from romania. Pdf chemical constituents and pharmacological activities. A particular emphasis is given on the organosulfur compounds contents, since they exert a great contribution to the effective bioactive properties of garlic, including its derived products. Sulfur compounds are the main chemical constituents responsible for allium sativums taste, smell, and likely for its biological effects. When a garlic clove is intact, glutamyl cysteins are the primary sulfur components powolyny and singh 2008 47. Oral, includes side effects, drug interactions, recommended dosages, and storage information. Chemical composition, antibacterial and antioxidant activities of tunisian garlic allium sativum essential oil and ethanol extract raja zouari chekki 1,2,3, ahmed snoussi 1,2, imen hamrouni 1 and nabiha bouzouita 1,2, 1 ecole superieure des industries alimentaires, 58 avenue alain savary, 1003 tunis, tunisia. Pdf chemical composition, phytochemical and mineral profile of. About allium cepa allium cepa effected for flu, sneezing, and coughing. Chemical composition and bioactive compounds of garlic allium sativum l. Allium sativum, commonly called garlic, is a bulbous perennial of the onion family. The essential oil content of dried coriander fruits varies between 0. Wild garlic, allium vineale, has been used as a substitute for garlic, both in food as well as in herbal medicine.
With regard to the chemical compositions of garlic allium sativum l. Research in recent decades has shown widespread pharmacological effects of a. The active properties of garlic depend on a pungent, volatile, essential oil. Natural products have been an integral part of ancient traditional medicine systems. The most important chemical constituents are the cysteine sulfoxides alliin and the nonvolatile glutamylcysteine peptides which make up more than 82% of the sulfur content of garlic. Chemical constituents of three allium species from romania laurian vlase 1, marcel parvu 2, elena alina parvu 3 and anca toiu 4 1 department of pharmaceutical technology and biopharmaceutics, faculty of pharmacy, iuliu hatieganu university of medicine and pharmacy, 12 ion creanga street. Studies of the chemical constituents of leaves of allium. Garlic, allium sativum, is broadly used around the world for its numerous culinary and medicinal uses. Allium is a genus of monocotyledonous flowering plants that includes hundreds of species, including the cultivated onion, garlic, scallion, shallot, leek, and chives. Chemical constituents of three allium species from romania laurian vlase 1, marcel parvu 2, elena alina parvu 3 and anca toiu 4. Garlic contains a higher concentration of sulfur compounds than any other allium species. The chemical composition of the antiinfluenza essential oils was phytochemically analyzed by gas chromatographymass spectrometry. Chemistry and pharmacology sulfur compounds are the main chemical constituents responsible for allium sativums taste, smell, and likely for its biological effects.
In the past few decades, its bioactive chemical constituents have been analyzed for their therapeutical properties. Chemical composition and bioactive compounds of garlic allium. Various factors that affect the chemical composition of garlic are involved in the production. The chemical constituents of garlic have also been investigated for treatment of cardiovascular disease, cancer, diabetes, blood pressure, atherosclerosis and hyperlipidaemia and highly praised by several authors. Study of phytochemical analysis and antioxidant activity of allium sativum of bundelkhand region vandana singh1, ramesh kumar2 1m. Growing garlic plants at wide plant density, and applying the higher npk rate resulted garlic allium sativum, l plant is an important crop grown in egypt for.
Plant essential oils are generally of quite complex composition containing. The result showed that the anticancer activity of allium sativum was due to dose and temporalrelated changes involved in the cancer process. Phytochemical screening and proximate analysis of garlic. The sulfur compounds are responsible both for garlics pungent odor and many of its medicinal effects. This paper is about the establishment of a micropropagation protocol of tunisian local garlic allium sativum l via apex sativum. Study of phytochemical analysis and antioxidant activity.
Historically, there has been great interest in the role and potential benefits of garlic in the management of diseases and maintenance of health. Pdf chemical composition and bioactive compounds of. The objective of the study was to investigate the phytochemical constituents and proximate composition of garlic a. Garlic has a measurable amount of germanium a mineral that. The qualitative phytochemical screening of allium sativum extracts is presented in table below table 2. Allium sativum and nilavembu andrographis paniculata toryali arify, s ezhilvalavan, a varun, a sundaresan and k manimaran abstract the present study investigates the qualitative analysis of the major bioactive constituents or phytochemical of medicinally important plant such as garlic allium sativum and nilavembu. The aim of this study was to analyze and clarify the chemical constituents of this spice essential oils. Chemical constituents and pharmacological properties of. Results the antiviral assays demonstrated that 11 of the 62 essential oils 100. Garlic allium sativum is a species in the onion genus, allium.
Chemical constituents and pharmacological activities of garlic allium sativum l. Health benefits of garlic depend on its content of biologicallyactive compounds, which differs between cultivars and geographical regions. The anticancer properties of fresh allium sativum extracts, aged allium sativum, allium sativum oil, and a number of specific organosulfur compounds was assessed. Quantitative phytochemical screening of allium sativum extract. The present study investigated the chemical compositions of a. Chemical constituents of essential oils possessing anti.
Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Student, department of biochemistry, bundelkhand university, jhansi, india 2associate prof. Authoritative and exhaustively compiled, medicinal plants of the world. Chemical constituents, traditional and modern medicinal uses, volume 1, 2nd edition offers pharmacists, physicians, medicinal chemists, toxicologists, and phytochemists a universal reference on twentysix of the most widely used medicinal plants in the world. Chemical characterization of the allium sativum and. Externally its used for nose eye ear and throat infections because of the thiamin content in it. Foliage consists of aromatic, linear, flattened, grasslike green leaves. Chief chemical constituent of garlic is an essential oil, which contains allyl propyl disulphide, diallyl disulphide, dimethyl disulphide and polysulphides. Allium sativum plant finder missouri botanical garden. The medicinal use of garlic allium sativum this is a natural medicinal plant use for disease prevention and it cures internally, its used against infection of all kinds.
Chemical constituents of allium stipitatum regel persian. Exhaustive extraction with water removes 80% of the total nitrogen of which 67% is in the nonprotein form, largely made up of compounds precipitable by phosphotungstic acid in 5% sulphuric acid. Consumer information about the medication garlic allium sativum l. Phytochemical and physicochemical characterization of allium. Garlic allium sativum is a source of medicine in many ways in human beings in routine life as well as in animals and its leaves, flowers, and cloves have been used in traditional medicine for a long time. Sampath kumar 1, debjit bhowmik 2, chiranjib 2, pankaj tiwari 2, rakesh kharel 2 1dept. Chemical composition and biological activity of allium sativum.
In the mid 1900s an american chemist named the strong smelling liquid allicin. Studies carried out on the chemical composition of the plant show that the most. It possess antidiabetic, antimicrobial, antihyperglycemic, antitumor, hepatoprotective, platelets inhibitory and antithrombic activities. Efficacy of crude extracts of garlic allium sativum. An investigation of the chemical composition, and the nitrogen partition in the nitrogen complex of the garlic allium sativum has been carried out. Allium cepa is usually thought of as a vegetable, it is also has a long history of medicinal use.
Research in recent decades has shown widespread pharmacological and therapeutic effects of a. Its close relatives include the onion, shallot, leek, chive, and chinese onion. Qualitative phytochemical analysis of garlic allium. Results showed strong antibiotic properties, and the complete absence of development. Chemical constituents of leaves of allium sativum l. Mainly the fleshy bulb that grows below the ground is used medicinally as well as for food but other parts of the plant also has a place in the traditional medicines. Garlic is native to central asia and northeastern iran, and has long been a common seasoning worldwide, with a history of several thousand years of human consumption and use. Characterization of active compounds of different garlic. Ali sn, al badawi mh, galhom ra, badr fm 2016 macroscopic and microscopic study of allium sativum garlic oil effects on post operative intraabdominal adhesion in. Stereochemical structure of the most representative bioactive constituents from allium sativum l alliin, allicin, allyl sulfide, e. The most representative bioactive properties of allicin from allium sativum l. Stereochemical structure of the most representative bioactive constituents from allium sativum l alliin, allicin, allyl sulfide, eajoene, zajoene and 1,2vinyldithiin.
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